The facts behind niacin

The facts behind niacin.

Although low-density lipoprotein cholesterol (LDL-C) lowering represents the mainstay of current lipid treatment, high-density lipoprotein cholesterol (HDL-C) has generated increasing interest as a secondary therapeutic target because of strong evidence that serum HDL-C concentration is inversely associated with coronary heart disease risk. Niacin is a lipid-altering drug that has been used to ...

Biochemical Facts behind the Definition and Properties of METABOLITES

The Myths and Facts behind Cyber Security Risks for Industrial Control Systems

Process control and SCADA systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. Unfortunately, new research indicates this complacency is misplaced – the move to open standards such as Ethernet, TCP/IP and web technologies is letting hackers take advantage of th...

English spelling is chaotic : What facts lie behind this popular judgment ?

In this talk I will investigate the popular idea that English spelling is chaotic, and consider how to teach English spelling. I will also assess the relationship between segmentation, reading and spelling. Spelling difficulties are due to the gap between orthography and pronunciation; a word represents both sound and meaning, and good spelling may improve students' overall performance.

Extended-release niacin/laropiprant: reducing niacin-induced flushing to better realize the benefit of niacin in improving cardiovascular risk factors.

Treatment with niacin effectively improves multiple lipid parameters and cardiovascular outcomes. Widespread use of niacin, however, is limited by flushing, which is mediated primarily by prostaglandin D2 (PGD2). Laropiprant is a selective PGD2 receptor 1 (DP1) antagonist that reduces objective measures of niacin-induced flushing symptoms upon initiation of therapy and with more chronic use. Re...